Aftab Nadeem Selected Research

Lactalbumin (alpha-Lactalbumin)

1/2021	Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex.
1/2019	Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET.
1/2017	HAMLET - A protein-lipid complex with broad tumoricidal activity.
11/2015	Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.
5/2015	The molecular motor F-ATP synthase is targeted by the tumoricidal protein HAMLET.
1/2014	Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).
10/2012	HAMLET: functional properties and therapeutic potential.

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Aftab Nadeem Research Topics

Disease

8	Neoplasms (Cancer) 03/2022 - 10/2012
6	Infections 01/2021 - 01/2016
3	Carcinoma (Carcinomatosis) 11/2021 - 05/2015
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 10/2012
2	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2014
1	Osteosarcoma (Osteogenic Sarcoma) 03/2022
1	Cholera 01/2021
1	Cystitis 10/2016
1	Bacterial Infections (Bacterial Infection) 01/2016
1	Blister (Bulla) 11/2015
1	Papilloma (Papillomatosis) 10/2012
1	Glioblastoma (Glioblastoma Multiforme) 10/2012

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 11/2021 - 10/2012
7	Lactalbumin (alpha-Lactalbumin)IBA 01/2021 - 10/2012
3	Pharmaceutical PreparationsIBA 03/2022 - 01/2017
2	CateninsIBA 01/2021 - 01/2014
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 05/2015
2	Oleic Acid (Oleate)IBA 01/2021 - 01/2019
2	LipidsIBA 01/2017 - 10/2012
2	Anti-Bacterial Agents (Antibiotics)IBA 02/2016 - 01/2016
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2022
1	MineralsIBA 03/2022
1	Durapatite (Hydroxylapatite)IBA 03/2022
1	Cytostatic AgentsIBA 03/2022
1	Bacterial Proteins (Bacterial Protein)IBA 01/2021
1	CathepsinsIBA 01/2021
1	CaspasesIBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	IronIBA 01/2020
1	Vancomycin FDA LinkGeneric 01/2020
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2019
1	LigandsIBA 01/2019
1	AntibodiesIBA 01/2019
1	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 01/2018
1	Substance PIBA 01/2018
1	Interleukin-1beta (Interleukin 1 beta)IBA 10/2016
1	Biomarkers (Surrogate Marker)IBA 10/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 10/2016
1	InflammasomesIBA 10/2016
1	Small Interfering RNA (siRNA)IBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA 01/2016
1	GTP Phosphohydrolases (GTPases)IBA 11/2015
1	Adenosine Triphosphate (ATP)IBA 05/2015
1	ChromatinIBA 05/2015
1	NucleotidesIBA 05/2015
1	Ion Channels (Ion Channel)IBA 01/2014
1	Biological ProductsIBA 01/2014
1	Therapeutic UsesIBA 10/2012

Therapy/Procedure

4	Therapeutics 01/2021 - 10/2012
2	Immunotherapy 10/2016 - 02/2016
1	Drug Therapy (Chemotherapy) 03/2022